Fluconazole solubility

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    Fluconazole solubility


    In New Zealand, fluconazole oral liquid is available and funded under Special Authority. Please refer to the Pharmaceutical Schedule Fluconazole has a solubility in water of 8 - 10mg per m L and is also soluble in ethanol. The injection is usually formulated in 0.9% Sodium Chloride and has a p H of tablets with deionised water. This preparation is chemically stable for 15 days at 4 and 23°C in glass vials. The potential for microbial growth was not assessed. Sterile water should be used for this preparation and a 7 day expiry date is suggested. Compatibility with flavours and syrups has not been assessed so a simple solution should be prepared as above. Antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration.

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    Is flconazole really soluble in water. in which tybe of water? should it warm or normal?can we dissolve it any other solvent like DMSO in place of water,to. Diflucan, Tablet, 150 mg/1, Oral, Lake Erie Medical Dba Quality Care Produts Llc, 1990-01-29, 2014-12-. water solubility, slightly soluble in water, FDA label. Fluconazole has a solubility in water of 8 - 10mg per mL and is also soluble in ethanol. The injection is usually formulated in 0.9% Sodium Chloride and has a.

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    Fluconazole solubility

    MSDS-Fluconazole Injection USP - Merit Pharm, Fluconazole DB00196 - Fluconazole - DrugBank

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  6. Fluconazole Properties. Melting point 138-140°C. Density 1.05. Flash point 9℃. storage temp. −20°C. solubility DMSO 5 mg/mL. form solid. pka pKa.

    • Fluconazole 86386-73-4 - ChemicalBook.
    • FLUCONAZOLE - Pharminfotech.
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    The solubility of Fluconazole in pure methanol, ethanol, propan-1-ol, butane-1-ol, chloroform, tetrahydrofuran, and 1,4-dioxane was measured by gravimetric method over a temperature range 298.15 to 323.15 K at atmospheric pressure. A stock solution may be made by dissolving the fluconazole in the solvent of choice. Fluconazole is soluble in organic solvents such as ethanol, DMSO, and. Fluconazole solubility in water is low 5.5 mg/mL but PG dissolves 147 ± 1.0 mg/mL and TCL 146 ± 5.9 mg/mL ; therefore, solubility in PG and TCL is similar and these two enhancers were selected for dissolution and incorporation of fluconazole into the four different topical dosage forms assayed.

     
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