Mikhail Varshavski, a board-certified family-medicine doctor in New York City (a.k.a. When we talk about these pills and patches and even scary-sounding IV drips that people swear by to stop feeling nauseous after drinking or to soothe their headache, what we’re really talking about are hangover And though there is some science to back up the claims of these hangover remedies, with so many options on the market, it can be hard to know which of these hangover cures is the right fit for you — and which ones will do the least damage. Directions: Those who swear by activated charcoal as a hangover remedy will often take two capsules before drinking. There are articles in the scientific literature that date back to the 1940s, examining the absorption power of activated charcoal, and activated charcoal is still sometimes used in emergency rooms to absorb specific poisons and deal with certain types of overdoses. In fact, when I asked the founder of the Alcohol Hangover Research Group, the only group of academic experts dedicated to demystifying the science of hangovers, to weigh in on the science behind various hangover pills and patches, the professor responded with a single line: “Currently, there is no hangover treatment available of which the effectiveness (or safety) is scientifically proven.” Part of the reason for the lack of a reliable hangover cure is because scientists still aren’t totally sure what a hangover is. It’s this whole host of symptoms that we loop into one category as hangovers,” explains Dr. He adds, “There’s one surefire hangover cure, and that’s time.” But that doesn’t mean hangover “cures” are all a total scam. Who Should Use It: anyone who worships at the altar of Moon Juice. How It Works: The idea is that the activated charcoal will filter out the toxins from your body, and that will, in turn, mitigate your hangover — and it’s not like that theory is totally without a scientific basis. So to help you make a better decision about the best way to fight your hangover (and figure out what you might be putting into your body), we took a deeper look into some of the most popular hangover cures on the market today. CPH (Cost Per Hangover): $0.14, when you buy a bottle of 100 capsules. One of the most commonly cited studies of activated charcoal’s ability to soak up excess booze is a 1981 study called “Effect of activated charcoal on ethanol blood levels in dogs,” in which six laboratory dogs were given alcohol, followed by activated charcoal. Mike explains, activated charcoal won’t actually prevent alcohol from being absorbed into the body. Who Should Use It: People whose main hangover symptom is a headache, or who didn’t plan on getting drunk the night before and don’t have time to sleep it off. The researchers found that the charcoal prevented the full absorption of the alcohol into the dogs’ bloodstreams, and the logic extended to humans. “Alcohol, once you drink it, it enters your bloodstream roughly in about an hour’s time and begins to get processed. Directions: When you wake up with a hangover, drop a tablet of Blowfish into a glass of water and drink. Hangover-Busting Ingredient: a combination of aspirin and clinical-grade caffeine. It doesn’t sit around in your stomach for a long period of time.” He’s also skeptical that alcohol binds to charcoal. I guess you can say if you’re actively drinking alcohol, and you don’t want to absorb some of it, you can take charcoal along with your alcohol — but then why are you drinking? Similar To: regular aspirin tablets and a cup of coffee. How It Works: Blowfish is designed to treat the symptoms of a hangover, especially the headache and fogginess that often come the morning after. “What seems to be going on with a hangover is that your body actually generates an inflammatory response, similar to a flu or a cold, so that’s why you have the achiness, the headache,” says founder Brenna Haysom. (The inclusion of aspirin, a nonsteroidal anti-inflammatory drug, or NSAID, is also why this is the only hangover treatment listed here that’s actually been approved by the U. Food and Drug Administration.) The caffeine, about as much as a half-cup of coffee per tablet, both helps the aspirin work better and wakes you up, since chances are good that you didn’t sleep too well. 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